TargetIQ
TargetIQby Bajpai Labs
Services

Four target intelligence capabilities. Built for portfolio gates.

Every engagement returns ranked targets with evidence dossiers plus the gate-ready documentation your committee needs to allocate budget.

Service 01

Multi-Omics Target Discovery

Identifying druggable disease targets with concordant genetic, expression, and pathway evidence across hundreds of candidates.

Timeline
2–3 weeks
Starting price
Engagements typically $75K–$200K per program
Process
  1. 01Ingest GWAS, bulk/scRNA-seq, proteomics, and client proprietary cohorts
  2. 02Knowledge-graph GNN scoring over gene–pathway–disease networks
  3. 03Genetic colocalization and Mendelian randomization causal scoring
  4. 04Deliver 8–15 priority targets with full evidence dossiers
Deliverable
Ranked target list + evidence dossiers + pathway maps + validation playbook
Service 02

Druggability & Safety Assessment

Filtering target lists by structural tractability, modality fit, and essential-gene safety before portfolio investment.

Timeline
1–2 weeks
Starting price
Engagements typically $50K–$125K per program
Process
  1. 01AlphaFold/PDB structural analysis and binding pocket scoring
  2. 02Modality fit assessment (small molecule, biologic, degrader, gene therapy)
  3. 03Essential-gene and tissue liability filtering (DepMap, GTEx, knockout phenotypes)
  4. 04Competitive landscape brief per target (trials, patents, approved drugs)
Deliverable
Druggability scores + safety tiers + competitive briefs per target
Service 03

Resistance Pathway Mapping

Mapping acquired resistance mechanisms and combination targets after targeted therapy failure in oncology.

Timeline
2–3 weeks
Starting price
Engagements typically $175K–$300K per program
Process
  1. 01Integrate post-progression biopsy RNA-seq with public resistance cohorts
  2. 02Resistance subtype clustering and pathway bypass detection via GNN
  3. 03Combination target scoring with synergy and orthogonality analysis
  4. 04Biomarker stratification panel for clinical protocol support
Deliverable
Resistance map + combination targets + biomarker panel + protocol appendix
Service 04

Portfolio Gate Decision Packages

Converting target analysis into investment-committee-ready deliverables with decision frameworks.

Timeline
1–2 weeks (often bundled with discovery)
Starting price
Engagements typically $100K–$250K per program
Process
  1. 01Assemble evidence dossiers with concordance tiers per target
  2. 02Build competitive white-space matrix and risk assessment
  3. 03Draft portfolio gate presentation with budget allocation recommendations
  4. 04Include validation roadmap and recommended experiments per priority target
Deliverable
Gate deck + dossier pack + decision framework + validation roadmap
Methodology

The science behind target ranking.

We compose published multi-omics methods with knowledge-graph GNNs and druggability scoring calibrated on portfolio gate outcomes.

Multi-omics fusion

GWAS, eQTL, scRNA-seq, proteomics cross-layer integration.

Knowledge-graph GNNs

Disease signal propagation over Reactome, STRING, and DisGeNET networks.

Druggability models

Structure, modality fit, and safety calibrated against approved drug precedents.

Pathway reconstruction

Bypass detection, resistance subtyping, and causal pathway mapping.

Custom & Enterprise Programs

Multi-indication franchise mapping, proprietary cohort integration, real-time collaboration with your bioinformatics team, and bespoke GNN training on internal knowledge graphs.

  • Multi-indication franchise mapping
  • Proprietary cohort integration
  • Real-time scientist collaboration
  • Custom knowledge-graph model training
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